Suffering of Man.

The man who…was forced into an oppressive narrowness and regularity of custom, impatiently tore himself apart, persecuted himself, gnawed away at himself, grew upset, and did himself damage…

With him was introduced the greatest and weirdest illness, from which human beings today have not recovered, the suffering of man from his own nature,, from himself, a consequence of the forcible separation form his animal past…a declaration of war against the old instincts, on which, up to that point, his power, joy, and ability to inspire fear has been based.

On the Genealogy of Morals